Alexia Pollack

Department of Biology University of Massachusetts-Boston 100 Morrissey Blvd. Boston, MA 02125 Phone: (617) 287-6618 Fax: (617) 287-6650 E-mail: alexia.pollack@umb.edu

Education

 

1991 Ph.D., Neuroscience, University of Virginia, Charlottesville, VA
1983 A.B., Biology, Barnard College, Columbia University, New York, NY

Research Experience

2000-present
Associate Professor
Dept. of Biology
University of Massachusetts-Boston

1995-2000
Assistant Professor
Dept. of Psychology,
Brown University, Providence, RI

1991-1995
Postdoctoral Fellow
Molecular Neurobiology Laboratory (Dr. J. Stephen Fink)
Massachusetts General Hospital and Harvard Medical School, Boston, MA

1986-1991
Dissertation Research
Dept. of Neuroscience (Dr. G. Frederick Wooten)
University of Virginia, Charlottesville, VA

Grants Awarded

2002-2004 AREA (R15) Award, NINDS, NIH
2001 Joseph P. Healey Endowment Grant and Proposal Development Award University of Massachusetts-Boston
1997-1998 American Parkinson Disease Association Award
1997, 1999 Brown University Small Grant Award
1991-1994 United Parkinson Foundation Award

Publications

Pollack, A.E., and Wooten, G.F. Effect of sodium on cell surface and intracellular 3H-naloxone binding sites. Life Sci. 41: (1987) 385-390.

Phillips, L.L., Pollack, A.E., and Steward, O. Protein synthesis in the neurophil of the rat dentate gyrus during synapse development. J. Neurosci. Res. 26: (1990) 474-482.

Pollack, A.E., and Wooten G.F. Differential regulation of striatal preproenkephalin mRNA by D1 and D2 dopamine receptors. Mol. Brain Res. 12: (1992) 111-119.

Pollack, A.E., and Wooten, G.F. D2 Dopaminergic regulation of striatal preproenkephalin mRNA levels is mediated in part through cholinergic interneurons. Mol. Brain Res. 13: (1992) 35-41.

Fink, J.S., Weaver, D.R., Rivkees, S.A., Peterfreund, R.A., Pollack, A.E., Adler, E.M., and Reppert, S.M. Molecular cloning of the rat A2 adenosine receptor: selective co-localization with D2 dopamine receptors in rat striatum. Mol. Brain Res. 14: (1992) 186-195.

Pollack, A.E., Harrison, M.B., Wooten, G.F., and Fink, J.S. Differential localization of A2a adenosine receptor mRNA with D1 and D2 dopamine receptor mRNA in striatal output pathways following a selective lesion of striatonigral neurons. Brain Res. 631: (1993) 161-166.

Konradi, C., Cole, R.L., Green, D., Senatus, P., Levesque, J.-C., Pollack, A.E., Grossbart, S.J., and Hyman, S.E. Analysis of the proenkephalin second messenger-inducible enhancer in rat striatal cultures. J. Neurochem. 65: (1995) 1007-1015.

Pollack, A.E., and Fink, J.S. Adenosine antagonists potentiate D2 dopamine-dependent activation of Fos in the striatopallidal pathway. Neuroscience 68: (1995) 721-728.

Turgeon, S.M., Pollack, A.E., Schusheim, L., and Fink, J.S. Effects of selective adenosine A1 and A2 agonists on amphetamine-induced locomotion and c-Fos in the striatum and nucleus accumbens. Brain Res. 707: (1996) 75-80.

Pollack, A.E., and Fink, J.S. Synergistic interaction between an adenosine antagonist and a D1 dopamine agonist on rotational behavior and striatal c-Fos induction in 6-hydroxydopamine lesioned rats. Brain Res. 743: (1996) 124-130.

Turgeon, S.M., Pollack, A.E., and Fink, J.S. Enhanced CREB phosphorylation and changes in c-Fos and FRA expression in striatum accompany amphetamine sensitization. Brain Res. 749: (1997) 120-126.

Pollack, A.E., Turgeon, S.M., and Fink, J.S. Apomorphine-priming alters the response of striatal outflow pathways to D2 agonist stimulation in 6-hydroxydopamine lesioned rats. Neuroscience 79: (1997) 70-93.

Pollack, A.E, Bird, J.L., Lambert, E.B., Florin, Z.P., and Castellar, V.L. Role of NMDA glutamate receptors in regulating D2 dopamine-dependent Fos induction in the rat striatopallidal pathway. Brain Res. 818: (1999) 543-547.

Pollack, A.E, and Strauss, J.B. Time dependence and role of NMDA glutamate receptors in the priming of D2-mediated rotational behavior and striatal Fos expression in 6-hydroxydopamine lesioned rats. Brain Res. 827: (1999) 160-168.

Pollack, A.E, and Yates, T.M. Prior D1 dopamine receptor stimulation is required to prime D2-mediated striatal Fos expression in 6-hydroxydopamine lesioned rats. Neuroscience 94: (1999) 505-514.

Pollack, A.E. and Haisley, E.C. NMDA glutamate receptor stimulation is required for the expression

of D2 dopamine mediated responses in apomorphine primed 6-hydroxydopamine lesioned rats. Brain Res. 897: (2001) 213-216.

Pollack, A.E. Basal Ganglia: Anatomy, Physiology and Pharmacology. Neurologic Clinics 19: (2001) 523-534